缺血性脑卒中患者血浆溶血磷脂酸水平的初步研究

被引：100

作者：

孙玉衡

伍期专

姚存姗

黄世昌

唐朝枢

李振光

包鹤丘

李松

周伟仅

机构：

[1] 首都医科大学附属北京积水潭医院神经内科,北京大学第一医院神经生化研究室,解放军医院神经内科,北京大学第一医院神经生化研究室,北京大学第一医院心血管病研究所,山东省威海市文登中心医院神经内科,北京大学第一医院神经生化研究室,首都医科大学附属北京积

来源：

中华医学杂志 | 2002年 / 04期

关键词：

脑缺血; 溶血磷脂酸类; 脑血管意外;

D O I：

暂无

中图分类号：

R743.3 [急性脑血管疾病（中风）];

学科分类号：

1002 ;

摘要：

目的　探讨短暂性脑供血不全发作 (TIA)和脑血栓形成以及疑似脑供血不全发作患者血浆溶血磷脂酸水平的变化。方法　采用有机溶剂抽提 ,并进一步分离出溶血磷脂酸 ,以定磷方法测定。结果　TIA和脑血栓形成以及疑似脑供血不全发作患者血浆溶血磷脂酸水平均显著高于对照组 (1 0 0 μmol/L± 0 70 μmol/L) ,分别为 2 14 μmol/L± 1 0 2 μmol/L、1 5 0 μmol/L± 0 85 μmol/L、1 73μmol/L± 1 14 μmol/L血浆 (P <0 0 5 )。经抗血小板聚集药物或抗凝血药物治疗患者血浆溶血磷脂酸水平下降。结论　作为体内凝血和血栓形成过程早期释放的分子标记物 ,血浆溶血磷脂酸可能在缺血性脑卒中诊断方面有重要应用前景

引用

页码：16 / 18

页数：3

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