MICROMETHOD FOR THE EMERGENCY ESTIMATION OF PLASMA PARACETAMOL CONCENTRATION USING HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY

被引：16

作者：

BUCHANAN, T

ADRIAENSSENS, P

STEWART, MJ

机构：

[1] UNIV EDINBURGH, DEPT CLIN CHEM, EDINBURGH EH3 9YW, MIDLOTHIAN, SCOTLAND

[2] UNIV EDINBURGH, DEPT CLIN PHYSIOL, EDINBURGH EH3 9YW, MIDLOTHIAN, SCOTLAND

[3] UNIV EDINBURGH, DEPT EXTRATERR PHYS, EDINBURGH EH3 9YW, MIDLOTHIAN, SCOTLAND

来源：

CLINICA CHIMICA ACTA | 1979年 / 99卷 / 02期

关键词：

D O I：

10.1016/0009-8981(79)90039-1

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

A method was developed for the emergency estimation of the antipyretic analgesic, paracetamol, using high performance liquid chromatography. The sample required is 100 .mu.l of human plasma. The use of a microcentrifuge reduces the total time for the estimation to 5 min from the receipt of the blood specimen. The method was compared with a standard UV method.

引用

页码：161 / 165

页数：5

共 11 条

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[2]

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[5]

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[6]

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[7] DETERMINATION OF ACETAMINOPHEN IN PHARMACEUTICAL PREPARATIONS AND BODY-FLUIDS BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY WITH ELECTROCHEMICAL DETECTION [J].

RIGGIN, RM ;

SCHMIDT, AL ;

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JOURNAL OF PHARMACEUTICAL SCIENCES, 1975, 64 (04) :680-683

[8]

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[9]

STEWART MJ, ANN CLIN BIOCH

[10] REVIEW OF METHODS FOR PLASMA PARACETAMOL ESTIMATION [J].

WIENER, K .

ANNALS OF CLINICAL BIOCHEMISTRY, 1978, 15 (JUL) :187-196

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