NITROSYL HEMOGLOBIN - NO-SPIN AS A RELAXATION PROBE IN SOLVENT PROTON MAGNETIC-RESONANCE EXPERIMENT DEMONSTRATING PHOSPHATE-INDUCED WIDENING OF HEME-POCKET

被引：9

作者：

BENKO, B ^{[1
]}

VUKPAVLOVIC, S ^{[1
]}

机构：

[1] UNIV ZAGREB, INST IMMUNOL, YU-41000 Zagreb, YUGOSLAVIA

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1976年 / 71卷 / 04期

关键词：

D O I：

10.1016/0006-291X(76)90796-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Nitric oxide bound to ferrous heme-Fe of Hb is a powerful relaxation probe in the solvent-PMR experiments. When such an experiment was applied to the interaction of human Hb with inositol hexaphosphate, it showed that phosphate increased the solvent-dynamics in the heme-pockets, consistent with their widening. Implications were discussed.

引用

页码：1303 / 1307

页数：5

共 23 条

[1] DYNAMICS OF LIGAND-BINDING TO MYOGLOBIN [J].