线栓法制备大鼠局灶性脑缺血再灌注模型的研究进展

被引：10

作者：

王志萍

曾因明

机构：

[1] 徐州医学院附属医院麻醉科

[2] 江苏省麻醉学重点实验室

来源：

国外医学麻醉学与复苏分册. | 2005年 / 03期

关键词：

局灶性脑缺血模型; 线栓法; 大鼠;

D O I：

暂无

中图分类号：

R-332 [医用实验动物学];

学科分类号：

1001 ;

摘要：

缺血性脑血管病的研究需要合适的动物模型,建立重复性好、结果可靠、稳定性强的动物模型一直是研究者追求的目标。颈内动脉线栓法制备大鼠局灶性脑缺血模型,无需开颅、重复性好、可准确控制缺血和再灌注时间,但仍有很多因素直接影响模型的成功率,给复制带来较大困难。现就模型复制过程需注意的环节和研究现状作一综述。

引用

页码：144 / 146

页数：3

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