血管性痴呆危险因素及发病机制的研究进展附视频

被引：104

作者：

高风超

陈翔

田新英

机构：

[1] 河北医科大学第二医院神经内科神经病学河北省重点实验室

来源：

医学综述 | 2014年 / 06期

关键词：

血管性痴呆; 危险因素; 发病机制;

D O I：

暂无

中图分类号：

R749.16 [];

学科分类号：

100203 ;

摘要：

血管性痴呆现已经成为一个重要的公共卫生问题,以缺血缺氧性或出血性脑损伤造成的病理组织学损伤和进行性智能减退为特征。血管性痴呆是仅次于阿尔茨海默病的第二大痴呆类型,其发病率逐年增加。血管性痴呆的确切的发病机制还不是很清楚,但目前公认脑缺血缺氧是血管性痴呆的主要病因。海马是学习记忆的重要结构,并且对脑缺血缺氧极其敏感。因此,脑缺血缺氧极易导致海马神经元凋亡,从而使学习记忆能力下降。目前,血管性痴呆是唯一一种可以防治的痴呆。因此,对血管性痴呆危险因素和发病机制的研究具有重要意义。

引用

页码：1068 / 1071

页数：4

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