踝肱指数和急性脑梗死患者脑微出血的相关性研究

被引：5

作者：

李传游

肖婧

丁彩霞

汤银燕

江雪梅

朱羽佳

胡丹

张兰坤

姜寒

盛蕾

机构：

[1] 南京中医药大学第二附属医院江苏省第二中医院神经内科

来源：

医学研究生学报 | 2017年 / 30卷 / 01期

关键词：

踝肱指数; 脑梗死; 脑微出血;

D O I：

暂无

中图分类号：

R743.3 [急性脑血管疾病（中风）];

学科分类号：

1002 ;

摘要：

目的踝肱指数(ABI)异常和心脑血管病事件的发生显著相关,但关于ABI水平与脑微出血(CMB)的相关性研究较少。文中旨在探讨异常ABI(≤0.9)和CMB发生及分布模式的相关性。方法连续纳入2015年1月至2015年12月入住于江苏省第二中医院神经内科诊断为脑梗死的患者187例。根据磁共振检查结果分为CMB阴性组115例和CMB阳性组72例(CMBs阳性)。根据CMB部位,又分为单纯脑叶组20例,深部CMB组24例,混合CMB组28例。单因素分析组间差异,同时多因素logistic回归分析ABI≤0.9与CMB的发生及分布的相关性。结果患者中ABI≤0.9者57例(30.5%)。与CMB阴性组ABI≤0.9发生率比较,CMB阳性组显著升高(22.6%vs 43.1%,P=0.003)。ABI水平和CMB数量存在显著负相关(r=-0.211,P=0.006)。多元logistic回归分析校正混杂因素后示:ABI≤0.9是缺血性脑血管病患者发生CMB(OR=2.363;95%CI:1.181～4.729)、深部CMB(OR=3.434;95%CI:1.283～9.187)及混合CMB(OR=2.837;95%CI:1.098～7.333)的危险因素。结论 ABI下降的急性脑梗死患者较易发生CMB,尤其是深部CMB。

引用

页码：57 / 60

页数：4

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