ASSIGNMENT OF THE GROWTH-HORMONE GENE LOCUS TO 19Q26-QTER IN CATTLE AND TO 11Q25-QTER IN SHEEP BY INSITU HYBRIDIZATION

被引：89

作者：

HEDIGER, R

JOHNSON, SE

BARENDSE, W

DRINKWATER, RD

MOORE, SS

HETZEL, J

机构：

[1] CSIRO, Molecular Genetics Group, Division of Tropical Animal Production, Rockhampton Mail Centre, QLD 4702

来源：

GENOMICS | 1990年 / 8卷 / 01期

关键词：

D O I：

10.1016/0888-7543(90)90241-L

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The growth hormone gene locus (GH) of cattle and sheep was mapped to a chromosomal region in each species by using in situ hybridization. The probe employed was an 830-bp cDNA sequence from the ovine growth hormone gene. Based on QFQ chromosome preparations, our results show that the GH locus is on cattle chromosome 19 in the region of bands q26-qter and in sheep on chromosome region 11q25-qter. The GH assignments together with previous localizations of type I cytokeratin genes (KRTA) and one homeobox (HOX2) gene in cattle and one type I cytokeratin gene (KRTA) in sheep identify a strongly conserved chromosomal segment on human chromosome 17, bovine chromosome 19, and sheep chromosome 11. © 1990.

引用

页码：171 / 174

页数：4

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