NEW GLYCOPEPTIDE IN PIG, OX AND SHEEP PITUITARY

被引：78

作者：

SMYTH, DG

MASSEY, DE

机构：

[1] National Institute for Medical Research, The Ridgeway, London, NW7 IAA, Mill Hill

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1979年 / 87卷 / 04期

关键词：

D O I：

10.1016/S0006-291X(79)80007-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A novel 39 residue glycopeptide has been isolated in substantial yield from pig, ox and sheep pituitary glands. The amino acid sequence is strongly conserved, suggesting that the peptide may fulfil an important role. The occurrence of two fragments of the pituitary glycopeptide which terminate in paired leucine residues reflects the action of a processing enzyme with previously unknown specificity. © 1979 Academic Press, Inc. All rights of reproduction in any form reserved.

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页码：1006 / 1010

页数：5

相关论文

共 10 条

[1]

BRADBURY AF, 1975, 4TH P AM PEPT S, P609

[2] CELL-FREE SYNTHESIS OF RAT PREPRO-INSULINS - CHARACTERIZATION AND PARTIAL AMINO-ACID SEQUENCE DETERMINATION [J].

CHAN, SJ ;

KEIM, P ;

STEINER, DF .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1976, 73 (06) :1964-1968

[3]

Graf L, 1970, Acta Biochim Biophys Acad Sci Hung, V5, P305

[4] GLYCOPEPTIDE FROM POSTERIOR LOBE OF PIG PITUITARIES .2. PRIMARY STRUCTURE [J].

HOLWERDA, DA .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1972, 28 (03) :340-&

[5] PRE-PROPARATHYROID HORMONE - ANALYSIS OF RADIOACTIVE TRYPTIC PEPTIDES AND AMINO-ACID SEQUENCE [J].

KEMPER, B ;

HABENER, JF ;

ERNST, MD ;

POTTS, JT ;

RICH, A .

BIOCHEMISTRY, 1976, 15 (01) :15-19

[6]

KREIL G, 1977, 11TH FEBS P, V47, P79

[7] NASCENT PRE-HORMONES ARE INTERMEDIATES IN BIOSYNTHESIS OF AUTHENTIC BOVINE PITUITARY GROWTH-HORMONE AND PROLACTIN [J].

LINGAPPA, VR ;

DEVILLERSTHIERY, A ;

BLOBEL, G .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1977, 74 (06) :2432-2436

[8] COMMON PRECURSOR TO CORTICOTROPINS AND ENDORPHINS [J].

MAINS, RE ;

EIPPER, BA ;

LING, N .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1977, 74 (07) :3014-3018

[9] CHARACTERIZATION OF A COMMON PRECURSOR TO CORTICOTROPIN AND BETA-LIPOTROPIN-IDENTIFICATION OF BETA-LIPOTROPIN PEPTIDES AND THEIR ARRANGEMENT RELATIVE TO CORTICOTROPIN IN PRECURSOR SYNTHESIZED IN A CELL-FREE SYSTEM [J].

ROBERTS, JL ;

HERBERT, E .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1977, 74 (12) :5300-5304

[10] ISOLATION OF C-FRAGMENT AND C'-FRAGMENT OF LIPOTROPIN FROM PIG PITUITARY AND C-FRAGMENT FROM BRAIN [J].

SMYTH, DG ;

SNELL, CR ;

MASSEY, DE .

BIOCHEMICAL JOURNAL, 1978, 175 (01) :261-270