PREVALENCE OF RAS GENE-MUTATIONS IN HUMAN COLORECTAL CANCERS

被引：1765

作者：

BOS, JL

FEARON, ER

HAMILTON, SR

VERLAANDEVRIES, M

VANBOOM, JH

VANDEREB, AJ

VOGELSTEIN, B

机构：

[1] JOHNS HOPKINS UNIV,SCH MED,CTR ONCOL,BALTIMORE,MD 21205

[2] JOHNS HOPKINS UNIV,SCH MED,DEPT PATHOL,BALTIMORE,MD 21205

[3] STATE UNIV LEIDEN,SYLVIUS LABS,DEPT MED BIOCHEM,2312 AV LEIDEN,NETHERLANDS

[4] STATE UNIV LEIDEN,SYLVIUS LABS,DEPT ORGAN CHEM,2312 AV LEIDEN,NETHERLANDS

来源：

NATURE | 1987年 / 327卷 / 6120期

关键词：

D O I：

10.1038/327293a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：293 / 297

页数：5

共 31 条

[1] MUTAGENS, ONCOGENES AND CANCER [J].

BARBACID, M .

TRENDS IN GENETICS, 1986, 2 (07) :188-192

[2] AMINO-ACID SUBSTITUTIONS AT CODON-13 OF THE N-RAS ONCOGENE IN HUMAN ACUTE MYELOID-LEUKEMIA [J].

BOS, JL ;

TOKSOZ, D ;

MARSHALL, CJ ;

VERLAANDEVRIES, M ;

VEENEMAN, GH ;

VANDEREB, AJ ;

VANBOOM, JH ;

JANSSEN, JWG ;

STEENVOORDEN, ACM .

NATURE, 1985, 315 (6022) :726-730

[3] A HUMAN GASTRIC-CARCINOMA CONTAINS A SINGLE MUTATED AND AN AMPLIFIED NORMAL ALLELE OF THE KI-RAS ONCOGENE [J].

BOS, JL ;

VERLAANDEVRIES, M ;

MARSHALL, CJ ;

VEENEMAN, GH ;

VANBOOM, JH ;

VANDEREB, AJ .

NUCLEIC ACIDS RESEARCH, 1986, 14 (03) :1209-1217

[4] 3 DIFFERENT MUTATIONS IN CODON-61 OF THE HUMAN N-RAS GENE DETECTED BY SYNTHETIC OLIGONUCLEOTIDE HYBRIDIZATION [J].

BOS, JL ;

VERLAANDEVRIES, M ;

JANSEN, AM ;

VEENEMAN, GH ;

VANBOOM, JH ;

VANDEREB, AJ .

NUCLEIC ACIDS RESEARCH, 1984, 12 (23) :9155-9163

[5] ACTIVATION OF KI-RAS 2 GENE IN HUMAN-COLON AND LUNG CARCINOMAS BY 2 DIFFERENT POINT MUTATIONS [J].

CAPON, DJ ;

SEEBURG, PH ;

MCGRATH, JP ;

HAYFLICK, JS ;

EDMAN, U ;

LEVINSON, AD ;

GOEDDEL, DV .

NATURE, 1983, 304 (5926) :507-513

[6]

COOPER GM, 1982, SCIENCE, V218, P801

[7] RISK OF COLORECTAL-CANCER IN ADENOMA-BEARING INDIVIDUALS WITHIN A DEFINED POPULATION [J].

EIDE, TJ .

INTERNATIONAL JOURNAL OF CANCER, 1986, 38 (02) :173-176

[8] ANALYSIS OF THE TRANSFORMING POTENTIAL OF THE HUMAN H-RAS GENE BY RANDOM MUTAGENESIS [J].

FASANO, O ;

ALDRICH, T ;

TAMANOI, F ;

TAPAROWSKY, E ;

FURTH, M ;

WIGLER, M .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1984, 81 (13) :4008-4012

[9] LOSS OF GENES ON THE SHORT ARM OF CHROMOSOME-11 IN BLADDER-CANCER [J].

FEARON, ER ;

FEINBERG, AP ;

HAMILTON, SH ;

VOGELSTEIN, B .

NATURE, 1985, 318 (6044) :377-380

[10] FREQUENCY OF MOLECULAR ALTERATIONS AFFECTING RAS PROTOONCOGENES IN HUMAN URINARY-TRACT TUMORS [J].

FUJITA, J ;

SRIVASTAVA, SK ;

KRAUS, MH ;

RHIM, JS ;

TRONICK, SR ;

AARONSON, SA .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (11) :3849-3853

← 1 2 3 4 →