DETERMINATION OF PROSTAGLANDIN-F2-ALPHA, PROSTAGLANDIN-E2, PROSTAGLANDIN-D2 AND PROSTAGLANDIN-6-KETO-F1-ALPHA IN HUMAN CEREBROSPINAL-FLUID

被引：39

作者：

ABDELHALIM, MS

EKSTEDT, J

ANGGARD, E

机构：

[1] UMEA UNIV,DEPT NEUROL,S-10485 UMEA,SWEDEN

[2] KAROLINSKA INST,DEPT PHARMACOL,S-10401 STOCKHOLM 60,SWEDEN

来源：

PROSTAGLANDINS | 1979年 / 17卷 / 03期

关键词：

D O I：

10.1016/S0090-6980(79)80008-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Prostaglandin (PG)F2α, E2, D2 and 6-keto-F1α were determined in human cerebrospinal fluid by a mass spectrometric technique. The samples were obtained from 12 patients with suspected intracranial disease. A 64 fold variation in PG levels was observed. The major PG was 6-keto-F1α (0.12-15 ng/ml). PGF2α and PGE2 were present in lower concentrations PGD2 was below the level of detection (0.05 ng/ml) except in one patient with extremely high total levels of PGs. © 1979.

引用

页码：405 / 409

页数：5

共 9 条

[1] IDENTIFICATION OF PROSTAGLANDIN D2 AS A MAJOR PROSTAGLANDIN IN HOMOGENATES OF RAT-BRAIN [J].