A PROSPECTIVE TOXICITY EVALUATION (COMPACT) ON 40 CHEMICALS CURRENTLY BEING TESTED BY THE NATIONAL-TOXICOLOGY-PROGRAM

被引：47

作者：

LEWIS, DFV

IOANNIDES, C

PARKE, DV

机构：

来源：

MUTAGENESIS | 1990年 / 5卷 / 05期

关键词：

D O I：

10.1093/mutage/5.5.433

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

引用

页码：433 / 435

页数：3

共 12 条

[1] CHEMICAL-STRUCTURE, SALMONELLA MUTAGENICITY AND EXTENT OF CARCINOGENICITY AS INDICATORS OF GENOTOXIC CARCINOGENESIS AMONG 222 CHEMICALS TESTED IN RODENTS BY THE UNITED-STATES NCI/NTP [J].

ASHBY, J ;

TENNANT, RW .

MUTATION RESEARCH, 1988, 204 (01) :17-115

[2] INDUCTION OF THE P-450-I FAMILY OF PROTEINS BY POLYCYCLIC AROMATIC-HYDROCARBONS - POSSIBLE RELATIONSHIP TO THEIR CARCINOGENICITY [J].

AYRTON, AD ;

MCFARLANE, M ;

WALKER, R ;

NEVILLE, S ;

COOMBS, MM ;

IOANNIDES, C .

TOXICOLOGY, 1990, 60 (1-2) :173-186

[3] THE INDUCTION OF P450-I PROTEINS BY AROMATIC-AMINES MAY BE RELATED TO THEIR CARCINOGENIC POTENTIAL [J].

AYRTON, AD ;

MCFARLANE, M ;

WALKER, R ;

NEVILLE, S ;

IOANNIDES, C .

CARCINOGENESIS, 1990, 11 (05) :803-809

[4] CYTOCHROME-P-448 AND THE ACTIVATION OF TOXIC-CHEMICALS AND CARCINOGENS [J].

IOANNIDES, C ;

LUM, PY ;

PARKE, DV .

XENOBIOTICA, 1984, 14 (1-2) :119-137

[5] MOLECULAR DIMENSIONS OF THE SUBSTRATE BINDING-SITE OF CYTOCHROME-P-448 [J].

LEWIS, DFV ;

IOANNIDES, C ;

PARKE, DV .

BIOCHEMICAL PHARMACOLOGY, 1986, 35 (13) :2179-2185

[6] MOLECULAR-ORBITAL STUDIES OF OXYGEN ACTIVATION AND MECHANISMS OF CYTOCHROMES-P-450-MEDIATED OXIDATIVE-METABOLISM OF XENOBIOTICS [J].

LEWIS, DFV ;

IOANNIDES, C ;

PARKE, DV .

CHEMICO-BIOLOGICAL INTERACTIONS, 1989, 70 (3-4) :263-280

[7] PREDICTION OF CHEMICAL CARCINOGENICITY FROM MOLECULAR AND ELECTRONIC-STRUCTURES - A COMPARISON OF MINDO/3 AND CNDO/2 MOLECULAR-ORBITAL METHODS [J].

LEWIS, DFV ;

IOANNIDES, C ;

PARKE, DV .

TOXICOLOGY LETTERS, 1989, 45 (01) :1-13

[8] STRUCTURAL REQUIREMENTS FOR SUBSTRATES OF CYTOCHROME-P-450 AND CYTOCHROME-P-448 [J].

LEWIS, DFV ;

IOANNIDES, C ;

PARKE, DV .

CHEMICO-BIOLOGICAL INTERACTIONS, 1987, 64 (1-2) :39-60

[9] REGULATION OF THE MAMMALIAN CYTOCHROME-P1-450 (CYP1A1) GENE [J].

NEBERT, DW ;

JONES, JE .

INTERNATIONAL JOURNAL OF BIOCHEMISTRY, 1989, 21 (03) :243-252

[10] METABOLIC-ACTIVATION OF CARCINOGENS AND TOXIC-CHEMICALS [J].

PARKE, DV ;

IOANNIDES, C ;

LEWIS, DFV .

HUMAN TOXICOLOGY, 1988, 7 (05) :397-404

← 1 2 →