CHANGES OF NEURON-SPECIFIC ENOLASE CONCENTRATION IN PLASMA AFTER CARDIAC-ARREST AND RESUSCITATION

被引：47

作者：

DAUBERSCHMIDT, R ^{[1
]}

ZINSMEYER, J ^{[1
]}

MROCHEN, H ^{[1
]}

MEYER, M ^{[1
]}

机构：

[1] HUMBOLDT UNIV,INST PATHOL & CLIN BIOCHEM,MED FAC CHARITE,O-1086 BERLIN,GERMANY

来源：

MOLECULAR AND CHEMICAL NEUROPATHOLOGY | 1991年 / 14卷 / 03期

关键词：

NEURON-SPECIFIC ENOLASE; BLOOD PLASMA; CARDIAC ARREST; RESUSCITATION; ISCHEMIC BRAIN DAMAGE;

D O I：

10.1007/BF03159939

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The concentration of neuron-specific enolase (NSE) was measured in plasma of 18 patients after cardiac arrest and resuscitation (14 nonsurvivors and 4 survivors). In all patients, the NSE concentration was significantly higher in comparison to reference values. The highest concentration was measured in nonsurvivors. Time-course investigation in the first 24 h after cardiac arrest was performed in five patients. Two nonsurvivors and one survivor of the five patients showed a significant rise, and a NSE peak concentration of 42.7-mu-g/L, 13.6-mu-g/L, and 10.5-mu-g/L, respectively, was found 10-19 h after cardiac arrest.

引用

页码：237 / 245

页数：9

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