CENTRAL MAMMALIAN NEURONS NORMALLY RESISTANT TO GLUTAMATE TOXICITY ARE MADE SENSITIVE BY ELEVATED EXTRACELLULAR CA-2+ - TOXICITY IS BLOCKED BY THE N-METHYL-D-ASPARTATE ANTAGONIST MK-801

被引：175

作者：

HAHN, JS

AIZENMAN, E

LIPTON, SA

机构：

[1] CHILDRENS HOSP MED CTR,DEPT NEUROL,300 LONGWOOD AVE,BOSTON,MA 02115

[2] HARVARD UNIV,SCH MED,PROGRAM NEUROSCI,BOSTON,MA 02115

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1988年 / 85卷 / 17期

关键词：

D O I：

10.1073/pnas.85.17.6556

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：6556 / 6560

页数：5

共 39 条

[1] RESPONSES MEDIATED BY EXCITATORY AMINO-ACID RECEPTORS IN SOLITARY RETINAL GANGLION-CELLS FROM RAT [J].

AIZENMAN, E ;

FROSCH, MP ;

LIPTON, SA .

JOURNAL OF PHYSIOLOGY-LONDON, 1988, 396 :75-91

[2] SELECTIVE DEPRESSION OF EXCITATORY AMINO-ACID INDUCED DEPOLARIZATIONS BY MAGNESIUM-IONS IN ISOLATED SPINAL-CORD PREPARATIONS [J].

AULT, B ;

EVANS, RH ;

FRANCIS, AA ;

OAKES, DJ ;

WATKINS, JC .

JOURNAL OF PHYSIOLOGY-LONDON, 1980, 307 (OCT) :413-428

[3] REPLICATION OF THE NEUROCHEMICAL CHARACTERISTICS OF HUNTINGTONS-DISEASE BY QUINOLINIC ACID [J].

BEAL, MF ;

KOWALL, NW ;

ELLISON, DW ;

MAZUREK, MF ;

SWARTZ, KJ ;

MARTIN, JB .

NATURE, 1986, 321 (6066) :168-171

[4]

BODMER WF, 1967, HISTOCOMPATIBILITY T

[5] BRAIN CALCIUM CONTENT IN ISCHEMIC INFARCTION [J].

CHEN, ST ;

HSU, CY ;

HOGAN, EL ;

JUAN, HY ;

BANIK, NL ;

BALENTINE, JD .

NEUROLOGY, 1987, 37 (07) :1227-1229

[6] GLUTAMATE NEUROTOXICITY IN CORTICAL CELL-CULTURE IS CALCIUM DEPENDENT [J].

CHOI, DW .

NEUROSCIENCE LETTERS, 1985, 58 (03) :293-297

[7]

CHOI DW, 1988, J NEUROSCI, V8, P185

[8]

CHOI DW, 1987, J NEUROSCI, V7, P369

[9] ANTICONVULSANT ACTIVITY OF (+)-5-METHYL-10, 11-DIHYDRO-5H-DIBENZO[A,D]CYCLOHEPTEN-5, 10-IMINE (MK-801), A SUBSTANCE WITH POTENT ANTICONVULSANT, CENTRAL SYMPATHOMIMETIC, AND APPARENT ANXIOLYTIC PROPERTIES [J].

CLINESCHMIDT, BV ;

MARTIN, GE ;

BUNTING, PR .

DRUG DEVELOPMENT RESEARCH, 1982, 2 (02) :123-134

[10] NMDA RECEPTORS - THEIR ROLE IN LONG-TERM POTENTIATION [J].

COLLINGRIDGE, GL ;

BLISS, TVP .

TRENDS IN NEUROSCIENCES, 1987, 10 (07) :288-293

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