EXPRESSION OF THYROID-HORMONE RECEPTOR BETA-2 IN RAT HYPOTHALAMUS

被引：103

作者：

COOK, CB ^{[1
]}

KAKUCSKA, I ^{[1
]}

LECHAN, RM ^{[1
]}

KOENIG, RJ ^{[1
]}

机构：

[1] NEW ENGLAND MED CTR HOSP, DIV ENDOCRINOL, BOSTON, MA 02111 USA

来源：

ENDOCRINOLOGY | 1992年 / 130卷 / 02期

关键词：

D O I：

10.1210/en.130.2.1077

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A polymerase chain reaction based assay was used to evaluate expression of thyroid hormone receptor beta-2 mRNA in rat hypothalamus. Expression was detected in the arcuate, ventromedial and paraventricular nuclei, as well as the median eminence. Trace expression was found in the dorsomedial nucleus, but no expression of thyroid hormone receptor beta-2 was detected in the lateral hypothalamus or the preoptic region. The results indicate that, contrary to previous belief, expression of thyroid hormone receptor beta-2 is not confined to the anterior pituitary.

引用

页码：1077 / 1079

页数：3

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