SINGLE-DOSE AND MULTIPLE-DOSE KINETICS OF ORAL LORAZEPAM IN HUMANS - PREDICTABILITY OF ACCUMULATION

被引：48

作者：

GREENBLATT, DJ

ALLEN, MD

MACLAUGHLIN, DS

HUFFMAN, DH

HARMATZ, JS

SHADER, RI

机构：

[1] MASSACHUSETTS MENTAL HLTH CTR,PSYCHOPHARMACOL RES LAB,BOSTON,MA 02115

[2] VET ADM HOSP,MED SERV,KANSAS CITY,MO 64128

[3] BOSTON COLLABORAT DRUG SURVEILLANCE PROGRAM,WALTHAM,MA 02154

来源：

JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS | 1979年 / 7卷 / 02期

关键词：

D O I：

10.1007/BF01059736

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：159 / 179

页数：21

共 26 条

[1] STATISTICAL ESTIMATIONS IN PHARMACOKINETICS [J].

BOXENBAU.HG ;

RIEGELMA.S ;

ELASHOFF, RM .

JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS, 1974, 2 (02) :123-148

[2]

BRODIE BB, 1949, J BIOL CHEM, V179, P25

[3]

Gibaldi M, 1975, PHARMACOKINETICS

[4]

Greenblatt D. J., 1974, BENZODIAZEPINES CLIN

[5]

Greenblatt D. J., 1978, PSYCHOPHARMACOLOGY G, P1381

[6] DRUG-THERAPY - CLINICAL PHARMACOKINETICS .1. [J].

GREENBLATT, DJ ;

KOCHWESER, J .

NEW ENGLAND JOURNAL OF MEDICINE, 1975, 293 (14) :702-705

[7] DRUG-THERAPY - CLINICAL PHARMACOKINETICS .2. [J].

GREENBLATT, DJ ;

KOCHWESER, J .

NEW ENGLAND JOURNAL OF MEDICINE, 1975, 293 (19) :964-970

[8] ANALYSIS OF LORAZEPAM AND ITS GLUCURONIDE METABOLITE BY ELECTRON-CAPTURE GAS-LIQUID-CHROMATOGRAPHY - USE IN PHARMACOKINETIC STUDIES OF LORAZEPAM [J].

GREENBLATT, DJ ;

FRANKE, K ;

SHADER, RI .

JOURNAL OF CHROMATOGRAPHY, 1978, 146 (02) :311-320

[9]

GREENBLATT DJ, 1978, INT J CLIN PHARM BI, V16, P486

[10]

GREENBLATT DJ, 1977, CLIN PHARMACOL THER, V21, P222

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