NONSTEROIDAL ANTIINFLAMMATORY DRUGS AND COMPLICATED DIVERTICULAR-DISEASE - A CASE CONTROL STUDY

被引：116

作者：

CAMPBELL, K ^{[1
]}

STEELE, RJC ^{[1
]}

机构：

[1] UNIV ABERDEEN, DEPT SURG, ABERDEEN AB9 1FX, SCOTLAND

来源：

BRITISH JOURNAL OF SURGERY | 1991年 / 78卷 / 02期

关键词：

D O I：

10.1002/bjs.1800780218

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Fifty patients with severe complications of diverticular disease were compared with two groups of 50 controls, matched for age and sex. The first control group (A) was randomly selected from all emergency hospital admissions, and the second group (B) from patients with uncomplicated diverticular disease. Of the 50 study patients, 24 (48 per cent) were taking non-steroidal anti-inflammatory drugs (NSAIDs) at the time of admission compared with nine (18 per cent) of control group A and ten (20 per cent) of control group B. Both of these differences were statistically significant, indicating a strong association between the ingestion of NSAIDs and the development of severe complications of diverticular disease.

引用

页码：190 / 191

页数：2

共 16 条

[1] NONSTEROIDAL ANTIINFLAMMATORY DRUGS AND GASTROINTESTINAL-BLEEDING - A CASE-CONTROL STUDY [J].

BARTLE, WR ;

GUPTA, AK ;

LAZOR, J .

ARCHIVES OF INTERNAL MEDICINE, 1986, 146 (12) :2365-2367

[2]

BJARNASON I, 1987, SCAND J RHEUMATOL, P55

[3] BENIGN ULCER OF SIGMOID COLON - AN UNUSUAL LESION THAT CAN SIMULATE CARCINOMA [J].

BRAVO, AJ ;

LOWMAN, RM .

RADIOLOGY, 1968, 90 (01) :113-&

[4] STEROIDS, NONSTEROIDAL ANTIINFLAMMATORY DRUGS, AND SERIOUS SEPTIC COMPLICATIONS OF DIVERTICULAR-DISEASE [J].

CORDER, A .

BRITISH MEDICAL JOURNAL, 1987, 295 (6608) :1238-1238

[5] ACUTE PERFORATION OF COLONIC DIVERTICULA ASSOCIATED WITH SHORT-TERM INDOMETHACIN [J].

COUTROT, S ;

ROLAND, D ;

BARBIER, J ;

VANDERMARCQ, P ;

ALCALAY, M ;

MATUCHANSKY, C .

LANCET, 1978, 2 (8098) :1055-1056

[6] INTESTINAL PERFORATION ASSOCIATED WITH OSMOTIC SLOW RELEASE INDOMETHACIN CAPSULES [J].

DAY, TK .

BRITISH MEDICAL JOURNAL, 1983, 287 (6406) :1671-1672

[7]

DEBENHAM GP, 1966, CAN MED ASSOC J, V94, P1182

[8] PROGRESS REPORT - ASPIRIN IN CHRONIC GASTRIC-ULCER - AUSTRALIAN EXPERIENCE [J].

DUGGAN, JM .

GUT, 1976, 17 (05) :378-384

[9]

HOFTIEZER JW, 1980, LANCET, V2, P609

[10] MEFENAMIC-ACID ENTEROPATHY [J].

ISAACS, PET ;

SLADEN, GE ;

FILIPE, I .

JOURNAL OF CLINICAL PATHOLOGY, 1987, 40 (10) :1221-1227

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