NITRERGIC INNERVATION OF THE RAT ESOPHAGUS - FOCUS ON MOTOR END-PLATES

被引：56

作者：

WORL, J ^{[1
]}

MAYER, B ^{[1
]}

NEUHUBER, WL ^{[1
]}

机构：

[1] GRAZ UNIV,DEPT PHARMACOL & TOXICOL,GRAZ,AUSTRIA

来源：

JOURNAL OF THE AUTONOMIC NERVOUS SYSTEM | 1994年 / 49卷 / 03期

关键词：

NITRIC OXIDE SYNTHASE; NADPH-DIAPHORASE; MOTOR END-PLATE; ENTERIC NERVOUS SYSTEM; ESOPHAGUS; RAT;

D O I：

10.1016/0165-1838(94)90169-4

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Nitric oxide synthase immunocytochemistry and correlated NADPH-diaphorase histochemistry were utilized to investigate nitrergic innervation of the rat esophagus. Almost all neuronal cell bodies and fibers around blood vessels, and in submucosa and mucosa which were immunoreactive for NOS, also co-stained for NADPH-diaphorase. A combined demonstration of motor endplates with tetramethylrhodamine a-bungarotoxin or calcitonin gene-related peptide immunocytochemistry demonstrated a nitrergic co-innervation of striated muscle fibers in all portions of the esophagus. The proportion of endplates co-stained increased from 35% to 78% from the cervical to the abdominal portion of the esophagus. These data indicate a role for NO in neuromuscular transmission in striated muscle of the esophagus.

引用

页码：227 / 233

页数：7

共 21 条

[1] COLOCALIZATION OF NITRIC-OXIDE SYNTHASE AND NADPH-DIAPHORASE IN THE MYENTERIC PLEXUS OF THE RAT GUT [J].