A STUDY OF DEVELOPMENT OF ADENOVIRUS ANTIGENS BY IMMUNOFLUORESCENT TECHNIQUE

被引：40

作者：

HAYASHI, K

RUSSELL, WC

机构：

[1] National Institute for Medical Research, London N.W.7, England

来源：

VIROLOGY | 1968年 / 34卷 / 03期

关键词：

D O I：

10.1016/0042-6822(68)90067-6

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

By using antisera which react specifically with different antigens in the capsid of adenovirus type 5 and an antiserum which can detect another type 5 antigen (designated P) which has many similarities to the T antigen associated with the oncogenic adenoviruses, a study has been made of the distribution and development of the fluorescent staining antigens in single-step infection by adenoviruses types 5, 7, and 12. The experiments suggest that the antigens detected by the P antiserum and by adenovirus type 12 tumour sera are a complex group of antigens at least one of which is group specific by the indirect immunofluorescent technique. The study also shows that this technique has a much wider specificity than other immunological methods used to characterize adenovirus types. © 1968.

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页码：470 / &

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