WIKTOR STENT IMPLANTATION IN PATIENTS WITH RESTENOSIS FOLLOWING BALLOON ANGIOPLASTY OF A NATIVE CORONARY-ARTERY

Intracoronary stenting has been introduced as an adjunct to balloon angioplasty aimed at overcoming its limitations, namely acute vessel closure and late restenosis. This study reports the first experience with the Wiktor(TM) stent implanted in the first 50 consecutive patients. All patiens had restenosis of a native coronary artery lesion after prior balloon angioplasty. The target coronary artery was the left anterior descending artery in 26 patients, the circumflex artery in 17 patients and the right coronary artery in 17 patients. The implantation success rate was 98% (49 of 50 patients). There were no procedural deaths. Acute or subacute thrombic stent occlusion occurred in 5 patients (10%). All 5 patients sustained a nonfatal acute myocardial infarction. Four of these patients underwent recanalization by means of balloon angioplasty; the remaining patient was referred for bypass surgery. A major bleeding complication occurred in 11 patients (22%): groin bleeding necessitating blood transfusion in 6, gastrointestinal bleeding in 3 and hematuria in 2. Repeat angiography was performed at a mean of 5.6 +/- 1.1 months in all but 1 patient undergoing implantation. Restenosis, defined by a reduction of greater-than-or-equal-to 0.72 mm in the minimal luminal diameter or a change in diameter stenosis from < to greater-than-or-equal-to 50%, occurred in 20 (45%) and 13 (29%) patients, respectively. In this first experience, the easiness and high technical success rate of Wiktor stent implantation are overshadowed by a high incidence of subacute stent occlusion and bleeding complications. Although direct comparison with balloon angioplasty regarding the incidence of subsequent restenosis rate is not possible, the experience reported in this study compares favorably with data reported in other published reports.