VALPROATE IN THE TREATMENT OF PARTIAL EPILEPSIES

被引：16

作者：

CHADWICK, D

机构：

[1] Department of Neurological Science, Walton Hospital, Liverpool

来源：

EPILEPSIA | 1994年 / 35卷

关键词：

ANTICONVULSANTS; VALPROATE; DRUG TOXICITY; CONTROLLED CLINICAL TRIALS;

D O I：

10.1111/j.1528-1157.1994.tb05980.x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Review of randomized controlled trials (RCTs) shows that valproate (VPA) is effective against partial seizures with or without becoming secondarily generalized. A number of RCTs show little difference in the efficacy of VPA and carbamazepine in this patient group, particularly where patients are randomized at the time of diagnosis. The length of time that it has taken to arrive at these conclusions emphasizes the importance of large active-controlled RCTs at an early stage in development in informing clinical practice.

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收藏

页码：S96 / S98

页数：3

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