PROTONATION OF METHOTREXATE BOUND TO THE CATALYTIC SITE OF DIHYDROFOLATE-REDUCTASE FROM LACTOBACILLUS-CASEI

被引：37

作者：

COCCO, L

TEMPLE, C

MONTGOMERY, JA

LONDON, RE

BLAKLEY, RL

机构：

[1] UNIV IOWA, DEPT BIOCHEM, IOWA CITY, IA 52242 USA

[2] UNIV CALIF LOS ALAMOS SCI LAB, LOS ALAMOS, NM 87545 USA

[3] SO RES INST, BIRMINGHAM, AL 35205 USA

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1981年 / 100卷 / 01期

关键词：

D O I：

10.1016/S0006-291X(81)80112-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：413 / 419

页数：7

共 16 条

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[2]

COCCO L, BIOCHEMISTRY

[3]

ERICKSON JS, 1972, J BIOL CHEM, V247, P5661

[4]

GLEISNER JM, 1975, J BIOL CHEM, V250, P1580

[5] DIHYDROFOLATE REDUCTASE FROM AMETHOPTERIN-RESISTANT LACTOBACILLUS-CASEI [J].

GUNDERSEN, LE ;

HARDING, NGL ;

FREISHEIM, JH ;

OTTING, F ;

HUENNEKENS, FM ;

DUNLAP, RB .

BIOCHEMISTRY, 1972, 11 (06) :1018-+

[6]

GUPTA VS, 1977, BIOCHEMISTRY-US, V16, P3073

[7] ULTRAVIOLET DIFFERENCE-SPECTROSCOPIC STUDIES OF SUBSTRATE AND INHIBITOR BINDING TO LACTOBACILLUS-CASEI DIHYDROFOLATE-REDUCTASE [J].

HOOD, K ;

ROBERTS, GCK .

BIOCHEMICAL JOURNAL, 1978, 171 (02) :357-366

[8]

MATTHEWS DA, 1978, J BIOL CHEM, V253, P6946

[9]

MONTGOMERY JA, 1971, ANN NY ACAD SCI, V186, P227

[10]

NIXON PF, 1968, J BIOL CHEM, V243, P4722

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