SOME EFFECTS OF ACCELERATED CHARGED PARTICLES ON BACTERIAL SPORES

被引:34
作者
POWERS, EL
LYMAN, JT
TOBIAS, CA
机构
[1] Laboratory of Radiation Biology, Department of Zoology, University of Texas, Austin
[2] Donner Laboratory, University of California, Berkeley
来源
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY AND RELATED STUDIES IN PHYSICS CHEMISTRY AND MEDICINE | 1968年 / 14卷 / 04期
基金
美国国家航空航天局;
关键词
D O I
10.1080/09553006814551171
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
Dry spores of Bacillus megaterium were irradiated with stripped atoms accelerated in the heavy ion linear accelerator. Nine different ions were used, each at 8·3 MeV/nucleon, with specific energy losses (LET) varying from 5 keV/μ (total) for the ionized deuteron up to 500 keV/μ for the Ne10+ ion. Survival curves were constructed for each ion in three experimental conditions allowing distinction among three classes of damage; class I, the completely oxygen-independent damage; class II, that seen only when oxygen is present during irradiation; and class III, that produced by interactions between oxygen and free radicals. Class I increased with increasing LET up to 190 keV/μ while classes II and III are constant in this range. Beyond this, II and III decrease to zero approximately at 500 keV/μ with I falling slightly. Cross-sectional values correspond with actual geometric dimensions of the spore: a high LET particle is lethal in any part of the protoplast; lower LET particles yield cross-sectional values that are smaller than morphologically distinct parts of the spore. A numerical analysis indicates two limiting cross-sections, one being possibly a single event process important at low LET, and the other a cooperative process that is the chief effect at high LET. © 1968 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
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页码:313 / &
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