GLUTATHIONE REDUCTASE-DEPENDENT METABOLISM OF CYSTEINE-S-SULFATE BY PENICILLIUM CHRYSOGENUM

被引：27

作者：

WOODIN, TS

SEGEL, IH

机构：

[1] Department of Biochemistry and Biophysics, University of California, Davis, CA

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1968年 / 167卷 / 01期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/0005-2744(68)90278-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A study of the metabolism of cysteine S-sulfate by Penicillium chrysogenum revealed that (a) cysteine-S-sulfate can serve as the sole sulfur source for the organism, (b) a sulfur-regulated permease mediates the transport of cysteine-S-sulfate into the cell and (c) a series of chemical exchange reactions coupled to glutathione reductase (NADPH: glutathione oxidoreductase, EC 1.6.4.2) (to regenerate reduced glutathione) could account for any net cysteine-S-sulfate utilization observable in vivo and in crude extracts. The proposed reactions are: {A figure is presented} and/or: {A figure is presented}. © 1968.

引用

页码：78 / &

共 27 条

[1] SPECIFICITY AND REGULATION OF METHIONINE TRANSPORT IN FILAMENTOUS FUNGI [J].