PROGRAMMED CELL-DEATH IN CAENORHABDITIS-ELEGANS

被引：324

作者：

HENGARTNER, MO ^{[1
]}

HORVITZ, HR ^{[1
]}

机构：

[1] MIT, HOWARD HUGHES MED INST, DEPT BIOL, CAMBRIDGE, MA 02139 USA

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1994年 / 4卷 / 04期

关键词：

D O I：

10.1016/0959-437X(94)90076-F

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Programmed cell death in the nematode Caenorhabditis elegans requires the activities of the genes ced-3 and ced-4 and is antagonized by the activity of the gene ced-9. Cloning of these C. elegans genes has shown that two of them encode proteins with similarity to vertebrate cell death genes and has revealed that nematodes and mammals share a common pathway for programmed cell death.

引用

页码：581 / 586

页数：6

共 45 条

[1] PRIMARY STRUCTURE OF THE HERPESVIRUS SAIMIRI GENOME [J].

ALBRECHT, JC ;

NICHOLAS, J ;

BILLER, D ;

CAMERON, KR ;

BIESINGER, B ;

NEWMAN, C ;

WITTMANN, S ;

CRAXTON, MA ;

COLEMAN, H ;

FLECKENSTEIN, B ;

HONESS, RW .

JOURNAL OF VIROLOGY, 1992, 66 (08) :5047-5058

[2] THE PROTOONCOGENE BCL-2 CAN SELECTIVELY RESCUE NEUROTROPHIC FACTOR-DEPENDENT NEURONS FROM APOPTOSIS [J].

ALLSOPP, TE ;

WYATT, S ;

PATERSON, HF ;

DAVIES, AM .

CELL, 1993, 73 (02) :295-307

[3] BCL-X, A BCL-2-RELATED GENE THAT FUNCTIONS AS A DOMINANT REGULATOR OF APOPTOTIC CELL-DEATH [J].

BOISE, LH ;

GONZALEZGARCIA, M ;

POSTEMA, CE ;

DING, LY ;

LINDSTEN, T ;

TURKA, LA ;

MAO, XH ;

NUNEZ, G ;

THOMPSON, CB .

CELL, 1993, 74 (04) :597-608

[4] MOLECULAR-CLONING OF THE INTERLEUKIN-1-BETA CONVERTING ENZYME [J].

CERRETTI, DP ;

KOZLOSKY, CJ ;

MOSLEY, B ;

NELSON, N ;

VANNESS, K ;

GREENSTREET, TA ;

MARCH, CJ ;

KRONHEIM, SR ;

DRUCK, T ;

CANNIZZARO, LA ;

HUEBNER, K ;

BLACK, RA .

SCIENCE, 1992, 256 (5053) :97-100

[5] CLONING AND STRUCTURAL-ANALYSIS OF CDNAS FOR BCL-2 AND A HYBRID BCL-2/IMMUNOGLOBULIN TRANSCRIPT RESULTING FROM THE T(14-18) TRANSLOCATION [J].

CLEARY, ML ;

SMITH, SD ;

SKLAR, J .

CELL, 1986, 47 (01) :19-28

[6] PREVENTION OF APOPTOSIS BY A BACULOVIRUS GENE DURING INFECTION OF INSECT CELLS [J].

CLEM, RJ ;

FECHHEIMER, M ;

MILLER, LK .

SCIENCE, 1991, 254 (5036) :1388-1390

[7]

DINARELLO CA, 1993, NEW ENGL J MED, V328, P106

[8] MOLECULAR-GENETICS OF CELL-DEATH IN THE NEMATODE CAENORHABDITIS-ELEGANS [J].

DRISCOLL, M .

JOURNAL OF NEUROBIOLOGY, 1992, 23 (09) :1327-1351

[9] GENETIC-CONTROL OF PROGRAMMED CELL-DEATH IN THE NEMATODE C-ELEGANS [J].

ELLIS, HM ;

HORVITZ, HR .

CELL, 1986, 44 (06) :817-829

[10]

FRITIG B, 1987, PLANT RESISTANCE VIR, P92

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