METABOLISM OF PROSTAGLANDINS IN RAT LIVER MITOCHONDRIA

被引：166

作者：

HAMBERG, M

机构：

[1] Institutionen for Medicinsk Kemi Kungl, Veterinärhöskolan, Stockholm

来源：

EUROPEAN JOURNAL OF BIOCHEMISTRY | 1968年 / 6卷 / 01期

关键词：

D O I：

10.1111/j.1432-1033.1968.tb00430.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A series of prostaglandins has been incubated with the β‐oxidizing enzyme system of rat liver. All of the compounds tested were oxidized. Prostaglandin E1, prostaglandin B1, prostaglandin F1α and prostaglandin F1β were converted into the corresponding C18 homologues. Prostaglandin A1, 11α,15‐dihydroxy‐9‐ketoprostanoic acid and 11α‐hydroxy‐9,15‐diketoprostanoic acid yielded mixtures of the C16 and C18 homologues. Nor‐prostaglandin F1α and homo‐prostaglandin F1α were both converted into trinor‐prostaglandin F1α. Copyright © 1968, Wiley Blackwell. All rights reserved

引用

页码：135 / &

共 24 条

[1]

ANGGARD E, 1964, J BIOL CHEM, V239, P4097

[2] PROSTAGLANDINS AND RELATED FACTORS .42. METABOLISM OF PROSTAGLANDIN E3 IN GUINEA PIG LUNG [J].