A BACTERIAL HOMOLOG TO HPRT

被引：2

作者：

BECKMAN, DL ^{[1
]}

KRANZ, RG ^{[1
]}

机构：

[1] WASHINGTON UNIV,DEPT BIOL,CAMPUS BOX NO 1137,ST LOUIS,MO 63130

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1991年 / 1129卷 / 01期

关键词：

HPRT; PHOTOSYNTHETIC BACTERIA; DNA SEQUENCE; PHOSPHORIBOSYLTRANSFERASE; LESCH-NYHAN SYNDROME;

D O I：

10.1016/0167-4781(91)90223-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The deduced 182 amino acid sequence of an open reading frame in the photosynthetic bacterium Rhodobacter capsulatus shows significant similarity to the hypoxanthine-guanine phosphoribosyltransferases of other organisms. This similarity includes conserved amino acid residues involved in Lesch-Nyhan syndrome.

引用

页码：112 / 114

页数：3

共 14 条

[1]

ARGOS P, 1983, J BIOL CHEM, V258, P6450

[2]

BECKMAN DL, IN PRESS EMJO J

[3] ANALYSIS OF CDNA-ENCODING THE HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE (HGPRTASE) OF SCHISTOSOMA-MANSONI - A PUTATIVE TARGET FOR CHEMOTHERAPY [J].

CRAIG, SP ;

MCKERROW, JH ;

NEWPORT, GR ;

WANG, CC .

NUCLEIC ACIDS RESEARCH, 1988, 16 (14) :7087-7101

[4]

DAVIDSON BL, 1991, AM J HUM GENET, V48, P951

[5]

DEVEREUX J, 1984, NUCLEIC ACIDS RES, V12, P187

[6] IDENTIFICATION OF MUTATIONS LEADING TO THE LESCH-NYHAN SYNDROME BY AUTOMATED DIRECT DNA SEQUENCING OF INVITRO AMPLIFIED CDNA [J].

GIBBS, RA ;

NGUYEN, PN ;

MCBRIDE, LJ ;

KOEPF, SM ;

CASKEY, CT .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1989, 86 (06) :1919-1923

[7] MULTIPLEX DNA DELETION DETECTION AND EXON SEQUENCING OF THE HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE GENE IN LESCH-NYHAN FAMILIES [J].

GIBBS, RA ;

NGUYEN, PN ;

EDWARDS, A ;

CIVITELLO, AB ;

CASKEY, CT .

GENOMICS, 1990, 7 (02) :235-244

[8] NUCLEOTIDE-SEQUENCE AND DEDUCED AMINO-ACID-SEQUENCE OF ESCHERICHIA-COLI ADENINE PHOSPHORIBOSYLTRANSFERASE AND COMPARISON WITH OTHER ANALOGOUS ENZYMES [J].

HERSHEY, HV ;

TAYLOR, MW .

GENE, 1986, 43 (03) :287-293

[9] ISOLATION AND CHARACTERIZATION OF A FULL-LENGTH EXPRESSIBLE CDNA FOR HUMAN HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE [J].

JOLLY, DJ ;

OKAYAMA, H ;

BERG, P ;

ESTY, AC ;

FILPULA, D ;

BOHLEN, P ;

JOHNSON, GG ;

SHIVELY, JE ;

HUNKAPILLAR, T ;

FRIEDMANN, T .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (02) :477-481

[10] CHARACTERIZATION OF CDNA CLONES FOR HYPOXANTHINE GUANINE PHOSPHORIBOSYLTRANSFERASE FROM THE HUMAN MALARIAL PARASITE, PLASMODIUM-FALCIPARUM - COMPARISONS TO THE MAMMALIAN GENE AND PROTEIN [J].

KING, A ;

MELTON, DW .

NUCLEIC ACIDS RESEARCH, 1987, 15 (24) :10469-10481

← 1 2 →