BIOSYNTHESIS OF COLLAGEN AND ITS DISORDERS .1.

被引：1040

作者：

PROCKOP, DJ

KIVIRIKKO, KI

TUDERMAN, L

GUZMAN, NA

机构：

[1] Department of Biochemistry, College of Medicine, Dentistry of New Jersey-Rutgers Medical School, University Heights, Piscataway

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 1979年 / 301卷 / 01期

关键词：

D O I：

10.1056/NEJM197907053010104

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

(First of Two Parts) COLLAGEN is the major macromolecule of most connective tissues, and it is widely believed that many human diseases, particularly chronic diseases, will be found to involve this protein either directly or indirectly. Since collagen biosynthesis was last reviewed in the Journal in 1972,1 much new information has been gained about the relatively complex pathway by which it is synthesized. We should like to consider this new information and some of its consequences in terms of the following questions: What is the structural information in the collagen molecule, and how does it determine the structure of the. © 1979, Massachusetts Medical Society. All rights reserved.

引用

页码：13 / 23

页数：11

共 134 条

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