DISTRIBUTION OF PNMT AND EPINEPHRINE IN THE MEDULLA-OBLONGATA OF NORMOTENSIVE AND SPONTANEOUS HYPERTENSIVE RATS

被引：39

作者：

LEW, JY

HATA, F

SAUTER, A

BABA, Y

ENGEL, J

GOLDSTEIN, M

机构：

[1] Department of Psychiatry, Neurochemistry Laboratories, New York Universit, Medical Center, New York

来源：

JOURNAL OF NEURAL TRANSMISSION | 1979年 / 44卷 / 04期

关键词：

D O I：

10.1007/BF01250326

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The distribution of the Epinephrine forming enzyme (PNMT) activity and Epinephrine (E) levels was investigated in the medulla oblongata of spontaneous hypertensive rats (SH-rats) and in two normotensive strains, namely Wistar Kyoto rats (WK-rats) and Wistar rats. The PNMT activity increases progressively from the caudal to rostral parts in the C1 and C2 regions of the medulla oblongata. The enzyme activity and the E levels are in all parts of the C1 and C2 regions higher in Wistar rats than in WK-rats. The PNMT activity in all parts of the C2 region (with the exception of the caudal region), and in the middle part of the C1 region is higher in SH-rats than in WK-rats. The E levels in the SH-rats are higher than in WK-rats in the mediocaudal parts of the C2 and C1 regions. © 1979 Springer-Verlag.

引用

页码：309 / 316

页数：8

共 14 条

[1] POSSIBLE INVOLVEMENT OF CENTRAL ADRENALIN NEURONS IN VASOMOTOR AND RESPIRATORY CONTROL - STUDIES WITH CLONIDINE AND ITS INTERACTIONS WITH PIPEROXANE AND YOHIMBINE [J].