INHIBITION OF BONE-FORMATION DURING SPACE-FLIGHT

被引：437

作者：

MOREY, ER

BAYLINK, DJ

机构：

[1] LAKE VET ADM HOSP,DEPT MED AMER,TACOMA,WA 98493

[2] UNIV WASHINGTON,SEATTLE,WA 98195

来源：

SCIENCE | 1978年 / 201卷 / 4361期

关键词：

D O I：

10.1126/science.150643

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Parameters of bone formation and resorption were measured in rats orbited for 19.5 days aboard the Soviet Cosmos 782 biological satellite. The most striking effects were on bone formation. During flight, rats formed significantly less periosteal bone than did control rats on the ground. An arrest line at both the periosteum and the endosteum of flight animals suggests that a complete cessation of bone growth occurred. During a 26-day postflight period, the defect in bone formation was corrected. No significant changes in bone resorption were observed. Copyright © 1978 AAAS.

引用

页码：1138 / 1141

页数：4

共 23 条

[1]

Anliker M, 1972, BIOMECHANICS ITS FDN, P237

[2] FORMATION, MINERALIZATION, AND RESORPTION OF BONE IN VITAMIN-D-DEFICIENT RATS [J].