EFFECT OF SATURABLE SERUM-PROTEIN BINDING ON THE PHARMACOKINETICS OF UNBOUND CEFONICID IN HUMANS

被引：25

作者：

DUDLEY, MN

SHYU, WC

NIGHTINGALE, CH

QUINTILIANI, R

机构：

[1] HARTFORD HOSP,DEPT PHARM,HARTFORD,CT 06115

[2] UNIV CONNECTICUT,SCH MED,STORRS,CT 06268

[3] UNIV CONNECTICUT,SCH PHARM,STORRS,CT 06268

[4] UNIV RHODE ISL,COLL PHARM,KINGSTON,RI 02881

[5] ROGER WILLIAMS GEN HOSP,DEPT PHARM,PROVIDENCE,RI 02908

[6] ROGER WILLIAMS GEN HOSP,DIV INFECT DIS,PROVIDENCE,RI 02908

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1986年 / 30卷 / 04期

关键词：

D O I：

10.1128/AAC.30.4.565

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

引用

页码：565 / 569

页数：5

共 21 条

[1]

BUNDTZEN RW, 1981, REV INFECT DIS, V3, P28

[2]

CHAMBERS MF, 1984, REV INFECT DIS S4, V6, pS870

[3] INVITRO ACTIVITY OF CEFONICID, CEFORANIDE, AND CEFAZOLIN AGAINST STAPHYLOCOCCUS-AUREUS AND STAPHYLOCOCCUS-EPIDERMIDIS AND THE EFFECT OF HUMAN-SERUM [J].

DUDLEY, MN ;

NIGHTINGALE, CH ;

QUINTILIANI, R ;

TILTON, RC .

JOURNAL OF INFECTIOUS DISEASES, 1983, 148 (01) :178-178

[4]

DUDLEY MN, 1984, CLIN PHARMACY, V3, P23

[5]

DUDLEY MN, 1982, NEW BETA LACTAM ANTI, P227

[6] INTEGRATION OF PHARMACOKINETICS AND PHARMACODYNAMICS OF METHICILLIN IN CURATIVE TREATMENT OF EXPERIMENTAL ENDOCARDITIS [J].

GENGO, FM ;

MANNION, TW ;

NIGHTINGALE, CH ;

SCHENTAG, JJ .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1984, 14 (06) :619-631

[7] PHARMACOKINETIC CONCEPTS - DRUG-BINDING, APPARENT VOLUME OF DISTRIBUTION AND CLEARANCE [J].

GIBALDI, M ;

KOUP, JR .

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 1981, 20 (04) :299-305

[8]

GIBALDI M, 1982, PHARMACOKINETICS

[9]

GOLDSTEIN A, 1949, PHARMACOL REV, V1, P102

[10]

JOOS RW, 1969, J PHARMACOL EXP THER, V166, P113

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