PHOSPHORYLATION OF ISOCITRATE DEHYDROGENASE OF ESCHERICHIA-COLI

被引：229

作者：

GARNAK, M ^{[1
]}

REEVES, HC ^{[1
]}

机构：

[1] ARIZONA STATE UNIV, DEPT BOT & MICROBIOL, TEMPE, AZ 85281 USA

来源：

SCIENCE | 1979年 / 203卷 / 4385期

关键词：

D O I：

10.1126/science.34215

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Addition of acetate to a stationary phase culture of E. coli in glycerol mineral salts medium containing 32P-labeled Pi results in rapid loss of isocitrate dehydrogenase [EC 1.1.1.42] activity and concomitant incorporation of 32P into the enzyme. This is the 1st example of protein phosphorylation in a bacterium in which the endogenous substrate for the protein kinase was identified.

引用

页码：1111 / 1112

页数：2

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