RESOLUTION OF TRIFLUOROMETHYLCARBINOLS

被引：29

作者：

FEIGL, DM

MOSHER, HS

机构：

[1] Department of Chemistry, Stanford University, Stanford

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1968年 / 33卷 / 11期

关键词：

D O I：

10.1021/jo01275a047

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

(±)-Phenyltrifluoromethylcarbinol and (±)-t-butyltrifluoromethylcarbinol have been resolved via the 3β-acetoxy- Δ6-etienate esters, but (±)-methyltrifluoromethylcarbinol could not be resolved by this method. The completeness of the resolution of the first compound was confirmed by a gas chromatographic study of its O-methylmandelate ester, and the enantiomeric purity of a partially active sample of the methyltrifluoromethylcarbinol was determined by the same method. This glpc method was not applicable to the determination of enantiomeric purity of t-butyltrifluoromethylcarbinol. © 1968, American Chemical Society. All rights reserved.

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页码：4242 / &

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