PARTIAL N-TERMINAL AMINO-ACID-SEQUENCE ANALYSES AND COMPARATIVE TRYPTIC PEPTIDE MAPS OF MURINE-IA MOLECULES ENCODED BY THE I-A SUBREGION

被引：31

作者：

CECKA, JM ^{[1
]}

MCMILLAN, M ^{[1
]}

MURPHY, DB ^{[1
]}

MCDEVITT, HO ^{[1
]}

HOOD, L ^{[1
]}

机构：

[1] CALTECH,DIV BIOL,PASADENA,CA 91125

来源：

EUROPEAN JOURNAL OF IMMUNOLOGY | 1979年 / 9卷 / 12期

关键词：

D O I：

10.1002/eji.1830091209

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The partial N‐terminal amino acid sequences and tryptic peptide maps of I‐A subregion products from the H‐2b, H‐2d, H‐2k and H‐2S haplotypes demonstrate that haplotype‐associated differences are present in both a and β polypeptides. The genetic and evolutionary implications of these multiple amino acid substitutions and the homology relationships among Ia molecules from human, guinea pig and the I‐E subregion of the mouse are discussed. Copyright © 1979 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim

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页码：955 / 963

页数：9

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