CLONING OF THE T-GENE REQUIRED IN MESODERM FORMATION IN THE MOUSE

被引：740

作者：

HERRMANN, BG

LABEIT, S

POUSTKA, A

KING, TR

LEHRACH, H

机构：

[1] NATL INST MED RES,MOLEC EMBRYOL LAB,LONDON NW7 1AA,ENGLAND

[2] EUROPEAN MOLEC BIOL LAB,W-6900 HEIDELBERG,GERMANY

[3] GERMAN CANC RES CTR,W-6900 HEIDELBERG 1,GERMANY

[4] UNIV WISCONSIN,GENET LAB,MADISON,WI 53706

[5] UNIV WISCONSIN,MCARDLE LAB CANC RES,MADISON,WI 53706

[6] IMPERIAL CANC RES FUND,LONDON WC2A 3PX,ENGLAND

来源：

NATURE | 1990年 / 343卷 / 6259期

关键词：

D O I：

10.1038/343617a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The murine developmental mutation T identifies an essential gene in mesoderm formation. Embryos lacking normal gene activity fail to form the notochord, the entire posterior region and the allan-tois, and die at about 10 days of gestation. We have isolated the T gene using a combination of molecular and genetic techniques, thus making molecular tools available to study processes underlying mesoderm formation in the mouse. © 1990 Nature Publishing Group.

引用

页码：617 / 622

页数：6

共 41 条

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