PHYSICAL MAPPING OF DRUG-RESISTANCE MUTATIONS DEFINES AN ACTIVE-CENTER OF THE HERPES-SIMPLEX VIRUS-DNA POLYMERASE ENZYME

被引：64

作者：

KNOPF, KW

KAUFMAN, ER

CRUMPACKER, C

机构：

[1] UNIV GLASGOW,INST VIROL,MRC,VIROL UNIT,GLASGOW G12 8QQ,SCOTLAND

[2] DEUTSCH KREBSFORSCHUNGSZENTRUM,INST VIRUSFORSCH,D-6900 HEIDELBERG,FED REP GER

[3] CHILDRENS HOSP MED CTR,DIV HUMAN GENET,BOSTON,MA 02115

[4] HARVARD UNIV,SCH MED,DEPT MICROBIOL & MOLEC GENET,BOSTON,MA 02115

[5] BETH ISRAEL HOSP,DEPT MED,DIV INFECT DIS,BOSTON,MA 02215

来源：

JOURNAL OF VIROLOGY | 1981年 / 39卷 / 03期

关键词：

D O I：

10.1128/JVI.39.3.746-757.1981

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

引用

页码：746 / 757

页数：12

共 29 条

[1] INHIBITION OF DEOXYRIBONUCLEIC-ACID POLYMERASES OF HUMAN-LEUKEMIC LEUKOCYTES BY 2',3'-DIDEOXYTHYMIDINE TRIPHOSPHATE [J].

ALLAUDEEN, HS .

BIOCHEMICAL PHARMACOLOGY, 1980, 29 (08) :1149-1153

[2] ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID .34. TERMINATION OF CHAIN GROWTH BY A 2',3'-DIDEOXYRIBONUCLEOTIDE [J].

ATKINSON, MR ;

DEUTSCHER, MP ;

KORNBERG, A ;

RUSSELL, AF ;

MOFFATT, JG .

BIOCHEMISTRY, 1969, 8 (12) :4897-+

[3] SYNTHESIS OF HERPES-SIMPLEX VIRUS, VACCINIA VIRUS, AND ADENOVIRUS DNA IN ISOLATED HELA-CELL NUCLEI .1. EFFECT OF VIRAL-SPECIFIC ANTISERA AND PHOSPHONOACETIC ACID [J].

BOLDEN, A ;

AUCKER, J ;

WEISSBACH, A .

JOURNAL OF VIROLOGY, 1975, 16 (06) :1584-1592

[4]

BOLLUM FJ, 1959, J BIOL CHEM, V234, P2733

[5] PHYSICAL MAPPING OF PAAR MUTATIONS OF HERPES-SIMPLEX VIRUS TYPE-1 AND TYPE-2 BY INTERTYPIC MARKER RESCUE [J].

CHARTRAND, P ;

STOW, ND ;

TIMBURY, MC ;

WILKIE, NM .

JOURNAL OF VIROLOGY, 1979, 31 (02) :265-276

[6] PHYSICAL AND GENETIC-ANALYSIS OF THE HERPES-SIMPLEX VIRUS-DNA POLYMERASE LOCUS [J].

CHARTRAND, P ;

CRUMPACKER, CS ;

SCHAFFER, PA ;

WILKIE, NM .

VIROLOGY, 1980, 103 (02) :311-326

[7] 2 DISTINCT LOCI CONFER RESISTANCE TO ACYCLOGUANOSINE IN HERPES-SIMPLEX VIRUS TYPE-1 [J].

COEN, DM ;

SCHAFFER, PA .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1980, 77 (04) :2265-2269

[8] RESISTANCE OF HERPES-SIMPLEX VIRUS TO ACYCLOGUANOSINE - GENETIC AND PHYSICAL ANALYSIS [J].

CRUMPACKER, CS ;

CHARTRAND, P ;

SUBAKSHARPE, JH ;

WILKIE, NM .

VIROLOGY, 1980, 105 (01) :171-184

[9] GROWTH-INHIBITION BY ACYCLOGUANOSINE OF HERPESVIRUSES ISOLATED FROM HUMAN INFECTIONS [J].

CRUMPACKER, CS ;

SCHNIPPER, LE ;

ZAIA, JA ;

LEVIN, MJ .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1979, 15 (05) :642-645

[10]

EDENBERG HJ, 1978, J BIOL CHEM, V253, P3273

← 1 2 3 →