Contiguous deletion syndromes

被引：68

作者：

Ballabio, Andrea ^{[1
]}

机构：

[1] Baylor Coll Med, Inst Mol Genet, One Baylor Plaza, Houston, TX 77030 USA

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1991年 / 1卷 / 01期

关键词：

D O I：

10.1016/0959-437X(91)80036-L

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

In the past few years, clinical, cytogenetic and molecular analysis of patients with complex phenotypes has led to the identification of syndromes caused by deletions of adjacent disease genes on a chromosome. These conditions, referred to as contiguous deletion syndromes, are an important component of the syndromes recognized in medical genetics, and the DNA from patients affected by these disorders is useful for the mapping and cloning of disease genes.

引用

页码：25 / 29

页数：5

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