PEROXIDATION OF SUBCELLULAR ORGANELLES - FORMATION OF LIPOFUSCINLIKE FLUORESCENT PIGMENTS

被引：220

作者：

CHIO, KS

REISS, U

FLETCHER, B

TAPPEL, AL

机构：

[1] Department of Food Science and Technology, University of California, Davis

来源：

SCIENCE | 1969年 / 166卷 / 3912期

关键词：

D O I：

10.1126/science.166.3912.1535

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Lipid peroxidation of subcellular organelles gives fluorescent products which have fluorescence and excitation spectra similar to those of lipofuscin pigments. Fluorescence and excitation spectra and total fluorescence in the 460-nanometer region are useful for qualitative identification and quantitative measurement of the Schiff base product, a molecular damage site of lipid peroxidation which develops during some aging processes.

引用

页码：1535 / &

共 20 条

[1]

Barber A A, 1967, Adv Gerontol Res, V2, P355

[2] INACTIVATION OF RIBONUCLEASE AND OTHER ENZYMES BY PEROXIDIZING LIPIDS AND BY MALONALDEHYDE [J].