MECHANISM OF CHYMOTRYPSIN - STRUCTURE, REACTIVITY, AND NONPRODUCTIVE BINDING RELATIONSHIPS

被引：107

作者：

FASTREZ, J ^{[1
]}

FERSHT, AR ^{[1
]}

机构：

[1] UNIV CAMBRIDGE,POSTGRAD MED SCH,MRC,LAB MOLEC BIOL,CAMBRIDGE CB2 2QH,ENGLAND

来源：

BIOCHEMISTRY | 1973年 / 12卷 / 06期

关键词：

D O I：

10.1021/bi00730a008

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：1067 / 1074

页数：8

共 34 条

[1] SPECIFICITY OF ALPHA-CHYMOTRYPSIN - DIPEPTIDE SUBSTRATES [J].

BAUMANN, WK ;

BIZZOZERO, SA ;

DUTLER, H .

FEBS LETTERS, 1970, 8 (05) :257-+

[2] DETERMINATION OF INDIVIDUAL RATE CONSTANTS OF ALPHA-CHYMOTRYPSIN-CATALYZED HYDROLYSIS WITH ADDED NUCLEOPHILIC AGENT, 1, 4-BUTANEDIOL [J].

BEREZIN, IV ;

KAZANSKAYA, NF ;

KLYOSOV, AA .

FEBS LETTERS, 1971, 15 (02) :121-+

[3] ON INTERACTION OF ACTIVE SITE OF ALPHA-CHYMOTRYPSIN WITH CHROMOPHORES - PROFLAVIN BINDING AND ENZYME CONFORMATION DURING CATALYSIS [J].

BERNHARD, SA ;

LEE, BF ;

TASHJIAN, ZH .

JOURNAL OF MOLECULAR BIOLOGY, 1966, 18 (03) :405-&

[4] MECHANISM OF AMINOLYSIS OF METHYL FORMATE [J].

BLACKBURN, GM ;

JENCKS, WP .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1968, 90 (10) :2638-+

[5]

BRANDT KG, 1967, J BIOL CHEM, V242, P3973

[6] USE OF SPECIFICITY CONSTANT OF ALPHA-CHYMOTRYPSIN [J].

BROT, FE ;

BENDER, ML .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1969, 91 (25) :7187-&

[7] CHYMOTRYPSIN CATALYSIS . EVIDENCE FOR A NEW INTERMEDIATE [J].

CAPLOW, M .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1969, 91 (13) :3639-&

[8] SELECTIVE ENZYME PURIFICATION BY AFFINITY CHROMATOGRAPHY [J].

CUATRECA.P ;

WILCHEK, M ;

ANFINSEN, CB .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1968, 61 (02) :636-&

[9]

FALLER LD, 1971, J BIOL CHEM, V246, P7446

[10] ACYL-TRANSFER REACTIONS OF AMIDES AND ESTERS WITH ALCOHOLS AND THIOLS - REFERENCE SYSTEM FOR SERINE AND CYSTEINE PROTEINASES - CONCERNING N PROTONATION OF AMIDES AND AMIDE-IMIDATE EQUILIBRIA [J].

FERSHT, AR .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1971, 93 (14) :3504-&

← 1 2 3 4 →