N-ACETYL GRAMICIDIN - SINGLE-CHANNEL PROPERTIES AND IMPLICATIONS FOR CHANNEL STRUCTURE

被引：73

作者：

SZABO, G

URRY, DW

机构：

[1] UNIV ALABAMA,MED CTR,MOLEC BIOPHYS LAB,BIRMINGHAM,AL 35294

[2] UNIV ALABAMA,MED CTR,CARDIOVASC RES & TRAINING CTR,BIRMINGHAM,AL 35294

来源：

SCIENCE | 1979年 / 203卷 / 4375期

关键词：

D O I：

10.1126/science.83000

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Substitution of a methyl group for the N-terminal hydrogen of gramicidin greatly increased the rate of dissociation of conductive channels in lipid bilayer membranes. The finding of short lifetimes for conductive channels, comparable to those seen for the neuromuscular junction, lends support to the head-to-head dimer structure for the conductive channel. Copyright © 1978 AAAS.

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页码：55 / 57

页数：3

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