WHAT IS THE TRUE CLINICAL-SIGNIFICANCE OF PLASMA-PROTEIN BINDING DISPLACEMENT INTERACTIONS

被引:62
作者
SANSOM, LN
EVANS, AM
机构
[1] School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, South, 5000, North Terrace
关键词
D O I
10.2165/00002018-199512040-00001
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
[No abstract available]
引用
收藏
页码:227 / 233
页数:7
相关论文
共 28 条
[1]  
Sellers E.M., Plasma protein displacement interactions are rarely of clinical significance, Pharmacology, 18, (1979)
[2]  
Rowland M., Tozer T., Clinical pharmacokinetics. Concepts and applications, (1989)
[3]  
Gibaldi M., Biopharmaceutics and clinical pharmacokinetics, (1991)
[4]  
Svensson C.K., Woodruff M.N., Lalka D., Influence of protein binding and use of unbound (free) drug concentrations, Applied pharmacokinetics. Principles of therapeutic drug monitoring, pp. 187-219, (1986)
[5]  
Stockley I.H., Drug interactions: a source book of adverse interactions, their mechanisms, clinical importance and management, (1981)
[6]  
Hansten P.D., Drug interactions: clinical significance of drug interactions, (1985)
[7]  
Prescott L.F., Clinically important drug interactions, Drug treatment, (1987)
[8]  
MacKichan J.J., Protein binding displacement interactions. Fact or fiction?, Clin Pharmacokinet, 16, pp. 65-73, (1989)
[9]  
du Souich P., Verges J., Erill S., Plasma protein binding and pharmacological response, Clin Pharmacokinet, 24, (1993)
[10]  
Rolan P.E., Plasma protein binding displacement interactions — why are they still regarded as clinically important?, Br J Clin Pharmacol, 37, (1994)