ACETYL-COA CARBOXYLASE FROM RAT ADIPOSE TISSUE

被引：44

作者：

DAKSHINA.K

DESJARDI.PR

机构：

[1] Department of Biochemistry, University of Manitoba

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1969年 / 176卷 / 02期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1016/0005-2760(69)90181-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Rat epididymal adipose tissue acetyl-CoA carboxylase activity has been shown to respond to various dietary treatments. Feeding a high dextrose diet increases the enzyme activity. In biotin-deficient rats the enzyme activity is reduced to less than a sixth of the levels found in control animals fed the deficient diet supplemented with biotin. Adipose tissue acetyl-CoA carboxylase is inhibited by both malonyl-CoA and coenzyme A. Unlike the liver enzyme, the adipose tissue carboxylase in not inactivated by cold treatment. © 1969.

引用

页码：221 / &

共 28 条

[1]

BLOCH K, 1960, LIPID METABOLISM ED, P1

[2]

BORTZ W, 1963, J BIOL CHEM, V238, P1226

[3] LIVER ACETYL COA CARBOXYLASE AND FATTY ACID SYNTHETASE - RELATIVE ACTIVITIES IN NORMAL STATE AND IN HEREDITARY OBESITY [J].