METABOLIC ACTIVATION OF 7-METHYLBENZ(A)ANTHRACENE IN MOUSE SKIN - HIGH TUMOR-INITIATING ACTIVITY OF 3,4-DIHYDRODIOL

被引：66

作者：

CHOUROULINKOV, I ^{[1
]}

GENTIL, A ^{[1
]}

TIERNEY, B ^{[1
]}

GROVER, P ^{[1
]}

SIMS, P ^{[1
]}

机构：

[1] ROYAL CANC HOSP,INST CANC RES,CHESTER BEATTY RES INST,LONDON SW3 6JB,ENGLAND

来源：

CANCER LETTERS | 1977年 / 3卷 / 5-6期

关键词：

D O I：

10.1016/S0304-3835(77)96163-8

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：247 / 253

页数：7

共 21 条

[1] TUMOR-INITIATING ACTIVITIES ON MOUSE SKIN OF DIHYDRODIOLS DERIVED FROM BENZO[A]PYRENE [J].

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BRITISH JOURNAL OF CANCER, 1976, 34 (05) :523-532

[2] INVOLVEMENT OF A DIOL-EPOXIDE IN METABOLIC ACTIVATION OF BENZO(A)PYRENE IN HUMAN BRONCHIAL-MUCOSA AND IN MOUSE SKIN [J].

GROVER, PL ;

HEWER, A ;

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INTERNATIONAL JOURNAL OF CANCER, 1976, 18 (01) :1-6

[3] IDENTIFICATION OF MUTAGENIC METABOLITES OF BENZO[A]PYRENE IN MAMMALIAN-CELLS [J].

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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1976, 73 (02) :607-611

[4] BENZO[A]PYRENE NUCLEIC ACID-DERIVATIVE FOUND INVIVO - STRUCTURE OF A BENZO[A]PYRENETETRAHYDRODIOL EPOXIDE-GUANOSINE ADDUCT [J].

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NAKANISHI, K .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1976, 98 (18) :5714-5715

[5]

JERINA DM, 1976, IN VITRO METABOLIC A, P159

[6] (+/-)-7ALPHA,8BETA-DIHYDROXY-9BETA,10BETA-EPOXY-7,8,9,10-TETRAHYDROBENZO[A]-PYRENE IS AN INTERMEDIATE IN METABOLISM AND BINDING TO DNA OF BENZO[A]PYRENE [J].

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OSBORNE, MR ;

BELAND, FA ;

HARVEY, RG ;

BROOKES, P .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1976, 73 (08) :2679-2681

[7] MUTAGENICITY OF NON-K-REGION DIOLS AND DIOL-EPOXIDES OF BENZ(A)ANTHRACENE AND BENZO(A)PYRENE IN S-TYPHIMURIUM TA-100 [J].

MALAVEILLE, C ;

BARTSCH, H ;

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SIMS, P .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1975, 66 (02) :693-700

[8] HIGH MICROSOME-MEDIATED MUTAGENICITY OF 3,4-DIHYDRODIOL OF 7-METHYLBENZ[A]ANTHRACENE IN S-TYPHIMURIUM TA98 [J].

MALAVEILLE, C ;

TIERNEY, B ;

GROVER, PL ;

SIMS, P ;

BARTSCH, H .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1977, 75 (02) :427-433

[9]

MALAVEILLE C, MUTAT RES

[10] MALIGNANT TRANSFORMATION AND MUTAGENESIS IN MAMMALIAN-CELLS INDUCED BY VICINAL DIOL-EPOXIDES DERIVED FROM BENZO(A)PYRENE [J].

MARQUARDT, H ;

BAKER, S ;

GROVER, PL ;

SIMS, P .

CANCER LETTERS, 1977, 3 (1-2) :31-36

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