GLUTAMATE RECEPTOR EXPRESSION IN THE RAT RETINA

被引：101

作者：

MULLER, F

GREFERATH, U

WASSLE, H

WISDEN, W

SEEBURG, P

机构：

[1] MAX PLANCK INST HIRNFORSCH,NEUROANAT ABT,DEUTSCHORDENSTR 46,W-6000 FRANKFURT 71,GERMANY

[2] UNIV HEIDELBERG,ZMBH,MOLEK NEUROENDOKRINOL LAB,W-6900 HEIDELBERG,GERMANY

来源：

NEUROSCIENCE LETTERS | 1992年 / 138卷 / 01期

关键词：

GLUTAMATE; GLUTAMATE RECEPTOR; RETINA; RAT; INSITU HYBRIDIZATION;

D O I：

10.1016/0304-3940(92)90500-7

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The expression of five genes (GluR A; B; C; D; GluR 5) encoding functional subunits of glutamate receptors was investigated in the rat retina using in situ hybridization with oligonucleotide probes. All five genes are expressed in the retina. All probes label cell bodies in the ganglion cell layer as well as somata in the inner third of the inner nuclear layer (INL), where the amacrine cells are located. In addition G]uR 5, B and D, and to a lesser extent also GluR A are found in the middle and outer part of the INL, where bipolar and horizontal cells reside. Different subsets of retinal neurons may thus use glutamate receptors of different subunit composition.

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页码：179 / 182

页数：4

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