HEAT-SHOCK, STRESS PROTEINS, CHAPERONES, AND PROTEOTOXICITY

Cold Spring Harbor was the scene of the first international heat shock meeting, held in 1982 on the 20th anniversary year of Ferruccio Ritossa's discovery of the heat shock response. Stimulated in part by the success of that first meeting, progress has been impressive: much of it was described at the meeting this spring at Cold Spring Harbor Laboratory, arranged by Richard Morimoto (Northwestern University) and Costa Georgopoulos (University of Utah), and entitled "Stress Proteins and The Heat Shock Response" (April 29-May 2, 1991). Judging from the numbers of new faces and the level of enthusiasm at this year's meeting, the progress is bound to continue (for comprehensive reviews of the field, see Morimoto et al., 1990;,Nover, 1991). © 1991.