RANDOMIZED COMPARISON OF RECOVERY AFTER PROPOFOL-NITROUS OXIDE VERSUS THIOPENTONE-ISOFLURANE-NITROUS OXIDE ANESTHESIA IN PATIENTS UNDERGOING AMBULATORY SURGERY

被引：87

作者：

KORTTILA, K ^{[1
]}

OSTMAN, P ^{[1
]}

FAURE, E ^{[1
]}

APFELBAUM, JL ^{[1
]}

PRUNSKIS, J ^{[1
]}

EKDAWI, M ^{[1
]}

ROIZEN, MF ^{[1
]}

机构：

[1] UNIV CHICAGO, DEPT ANESTHESIA & CRIT CARE, CHICAGO, IL 60637 USA

来源：

ACTA ANAESTHESIOLOGICA SCANDINAVICA | 1990年 / 34卷 / 05期

关键词：

Anesthesia: outpatient; anesthetic techniques: general; anesthetics; complications: nausea; intravenous: propofol; recovery: assessment; thiopentone; volatile: isoflurane; vomiting;

D O I：

10.1111/j.1399-6576.1990.tb03111.x

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

A randomized, prospective study was performed to compare recovery characteristics in 41 ASA physical status I‐II patients scheduled for ambulatory surgery with either propofol or thiopentone‐isoflurane anaesthesia. Particular attention was focused on the recovery time needed to meet discharge criteria. The propofol group received propofol 2 mg · kg‐1 for induction followed by propofol infusion (6–9 mg · kg‐1 · h‐1) 1 min after intubation. The thiopentone‐isoflurane group received thiopentone 4 mg · kg‐1 for induction followed by isoflurane (0.5–2%) 1 min after endotracheal intubation. Other drugs administered during or after anaesthesia were similar between the groups. The propofol group had significantly (P<0.05) faster clinical recovery than the isoflurane group with respect to times to response to commands, eye opening, orientation, ability to stand and void, tolerance to oral fluids, “home‐readiness”, and recovery of perceptual speed. Patients in the propofol group had significantly less (P<0.05) emesis than the patients given isoflurane. We conclude that in patients undergoing ambulatory surgery propofol infusion is preferable to thiopentoneisoflurane anaesthesia, because it may allow faster discharge home. © 1990 Acta Anaesthesiologica Scandinavica Fonden

引用

页码：400 / 403

页数：4

共 17 条

[1]

ALDRETE JA, 1970, ANESTH ANAL CURR RES, V49, P924

[2] MONITORING OF NEUROMUSCULAR FUNCTION [J].

ALI, HH ;

SAVARESE, JJ .

ANESTHESIOLOGY, 1976, 45 (02) :216-249

[3]

COATES DP, 1987, ANESTH ANALG, V66, P64

[4] PHARMACOKINETICS OF PROPOFOL IN FEMALE-PATIENTS - STUDIES USING SINGLE BOLUS INJECTIONS [J].

COCKSHOTT, ID ;

BRIGGS, LP ;

DOUGLAS, EJ ;

WHITE, M .

BRITISH JOURNAL OF ANAESTHESIA, 1987, 59 (09) :1103-1110

[5] PROPOFOL NITROUS OXIDE VERSUS THIOPENTAL-ISOFLURANE NITROUS OXIDE FOR GENERAL-ANESTHESIA [J].

DOZE, VA ;

SHAFER, A ;

WHITE, PF .

ANESTHESIOLOGY, 1988, 69 (01) :63-71

[6]

Gepts E, 1988, Anaesthesia, V43 Suppl, P8, DOI 10.1111/j.1365-2044.1988.tb09060.x

[7] DISPOSITION OF PROPOFOL IN PATIENTS UNDERGOING SURGERY - A COMPARISON IN MEN AND WOMEN [J].

KAY, NH ;

SEAR, JW ;

UPPINGTON, J ;

COCKSHOTT, ID ;

DOUGLAS, EJ .

BRITISH JOURNAL OF ANAESTHESIA, 1986, 58 (10) :1075-1079

[8] POSTANESTHETIC COGNITIVE AND PSYCHOMOTOR IMPAIRMENT [J].

KORTTILA, K .

INTERNATIONAL ANESTHESIOLOGY CLINICS, 1986, 24 (04) :59-74

[9]

KORTTILA K, 1988, PROBL ANESTH, V2, P144

[10]

MCCOLLUM JSC, 1988, ANAESTHESIA, V43, P239

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