GAMMA-DELTA T-CELL RECEPTOR POSITIVE T-CELL CLONES DERIVED FROM HUMAN HEART-TRANSPLANTS DO NOT SHOW DONOR-SPECIFIC CYTOTOXICITY

被引：10

作者：

JUTTE, NHPM

VANDEKERCKHOVE, BAE

VAESSEN, LMB

OUWEHAND, AJ

BAAN, CC

BOS, E

CLAAS, FHJ

WEIMAR, W

机构：

[1] ERASMUS UNIV, HOSP DIJKZIGT, DEPT THORAC SURG, 3000 DR ROTTERDAM, NETHERLANDS

[2] STATE UNIV LEIDEN HOSP, DEPT IMMUNOHAEMATOL, 2333 AA LEIDEN, NETHERLANDS

[3] STATE UNIV LEIDEN HOSP, BLOOD BANK, 2333 AA LEIDEN, NETHERLANDS

来源：

HUMAN IMMUNOLOGY | 1990年 / 28卷 / 02期

关键词：

D O I：

10.1016/0198-8859(90)90015-H

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

γδ T-cell receptor-positive T-cell clones were obtained from three endomyocardial biopsies taken from two patients. Clones obtained from two biopsies from patient A, one taken during rejection and one after resolution of this rejection, were WT31-, 11F2+, TiγA-, δTcS1+. Clones from patient B grown from a biopsy without histologic signs of rejection were either WT31-, 11F2+, TiγA+, δTcS1-, or WT31+. All γδ T-cell receptor-positive clones had cytolytic potential but did not demonstrate donor-specific lysis. © 1990.

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收藏

页码：170 / 174

页数：5

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