SEX-CHROMOSOMES, RECOMBINATION, AND CHROMATIN CONFORMATION

被引：247

作者：

MCKEE, BD

HANDEL, MA

机构：

[1] Department of Zoology, University of Tennessee, Knoxville, 37996, TN

来源：

CHROMOSOMA | 1993年 / 102卷 / 02期

关键词：

D O I：

10.1007/BF00356023

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We review what is known about the transcriptional inactivation and condensation of heteromorphic sex chromosomes in contrast to the activation of homomorphic sex chromosomes during meiotic prephase in animals. We relate these cytological and transcriptional features to the recombination status of the sex chromosomes. We propose that sex chromosome condensation is a meiotic adaptation to prevent the initiation of potentially damaging recombination events in nonhomologous regions of the X and Y chromosome.

引用

页码：71 / 80

页数：10

共 121 条

[1] STUDY OF X-CHROMOSOME REGULATION DURING OOGENESIS IN MOUSE [J].