The molecular biology of the CNTF receptor

被引：35

作者：

Davis, Samuel ^{[1
]}

Yancopoulos, George D. ^{[1
]}

机构：

[1] Regeneron Pharmaceut Inc, Tarrytown, NY 10591 USA

来源：

CURRENT OPINION IN CELL BIOLOGY | 1993年 / 5卷 / 02期

关键词：

D O I：

10.1016/0955-0674(93)90117-9

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Recently there have been advances in studies of the molecular biology of the receptor for CNTF. In contrast with the receptors for other known neurotrophic factors, which belong to the family of receptor tyrosine kinases, the CNTF receptor belongs to the family of cytokine receptors. This review will describe the structural features and signaling capabilities of the CNTF receptor, and discuss the implications for the biology of CNTF as well as for other neurotrophic factors and cytokines. This review is an updated version of the review that appears in Current Opinion in Neurobiology 1993, 3:20-24.

引用

收藏

页码：281 / 285

页数：5

相关论文

共 31 条

[1]

BAUMANN M, 1990, J BIOL CHEM, V265, P19853

[2] NEUROPOIETIC CYTOKINES IN THE HEMATOPOIETIC FOLD [J].

BAZAN, JF .

NEURON, 1991, 7 (02) :197-208

[3] THE RECEPTOR FOR CILIARY NEUROTROPHIC FACTOR [J].

DAVIS, S ;

ALDRICH, TH ;

VALENZUELA, DM ;

WONG, V ;

FURTH, ME ;

SQUINTO, SP ;

YANCOPOULOS, GD .

SCIENCE, 1991, 253 (5015) :59-63

[4]

DAVIS S, 1993, SCIENCE IN PRESS

[5] REGULATION OF CILIARY NEUROTROPHIC FACTOR EXPRESSION IN MYELIN-RELATED SCHWANN-CELLS INVIVO [J].

FRIEDMAN, B ;

SCHERER, SS ;

RUDGE, JS ;

HELGREN, M ;

MORRISEY, D ;

MCCLAIN, J ;

WANG, DY ;

WIEGAND, SJ ;

FURTH, ME ;

LINDSAY, RM ;

IP, NY .

NEURON, 1992, 9 (02) :295-305

[6] HOMOLOGY OF THE P40 SUBUNIT OF NATURAL-KILLER-CELL STIMULATORY FACTOR (NKSF) WITH THE EXTRACELLULAR DOMAIN OF THE INTERLEUKIN-6 RECEPTOR [J].

GEARING, DP ;

COSMAN, D .

CELL, 1991, 66 (01) :9-10

[7] THE IL-6 SIGNAL TRANSDUCER, GP130 - AN ONCOSTATIN-M RECEPTOR AND AFFINITY CONVERTER FOR THE LIF RECEPTOR [J].

GEARING, DP ;

COMEAU, MR ;

FRIEND, DJ ;

GIMPEL, SD ;

THUT, CJ ;

MCGOURTY, J ;

BRASHER, KK ;

KING, JA ;

GILLIS, S ;

MOSLEY, B ;

ZIEGLER, SF ;

COSMAN, D .

SCIENCE, 1992, 255 (5050) :1434-1437

[8] LEUKEMIA INHIBITORY FACTOR RECEPTOR IS STRUCTURALLY RELATED TO THE IL-6 SIGNAL TRANSDUCER, GP130 [J].

GEARING, DP ;

THUT, CJ ;

VANDENBOS, T ;

GIMPEL, SD ;

DELANEY, PB ;

KING, J ;

PRICE, V ;

COSMAN, D ;

BECKMANN, MP .

EMBO JOURNAL, 1991, 10 (10) :2839-2848

[9] INTERACTION OF THE IL-2 RECEPTOR WITH THE SRC-FAMILY KINASE-P56LCK - IDENTIFICATION OF NOVEL INTERMOLECULAR ASSOCIATION [J].

HATAKEYAMA, M ;

KONO, T ;

KOBAYASHI, N ;

KAWAHARA, A ;

LEVIN, SD ;

PERLMUTTER, RM ;

TANIGUCHI, T .

SCIENCE, 1991, 252 (5012) :1523-1528

[10] MOLECULAR-CLONING AND EXPRESSION OF AN IL-6 SIGNAL TRANSDUCER, GP130 [J].

HIBI, M ;

MURAKAMI, M ;

SAITO, M ;

HIRANO, T ;

TAGA, T ;

KISHIMOTO, T .

CELL, 1990, 63 (06) :1149-1157

← 1 2 3 4 →