PREVALENCE OF AGE-ASSOCIATED MEMORY IMPAIRMENT AND DEMENTIA IN A RURAL-COMMUNITY

被引:92
作者
CORIA, F
DECASO, JAG
MINGUEZ, L
RODRIGUEZARTALEJO, F
CLAVERIA, LE
机构
[1] TUREGANO HLTH CTR,SEGOVIA,SPAIN
[2] UNIV AUTONOMA MADRID,DEPT PREVENT MED,MADRID 34,SPAIN
关键词
D O I
10.1136/jnnp.56.9.973
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
To obtain accurate estimates of the prevalence of age-associated memory impairment, dementia, and Alzheimer's disease, a population study was carried out in Turegano, a rural community of 1011 inhabitants in the Segovia province of Spain. The study was divided into two phases: a door to door survey of the entire population aged 40 years and over (503 persons), followed by a clinical examination of suspected cases for positive and differential diagnosis of dementia and cognitive impairment. The prevalence of age-associated memory impairment was 3.6% in individuals of 40 years and over and 7.1% in individuals of 65 years and over, whereas dementia was found in 2.6% and 5-2%, respectively. The prevalence rates of both clinical conditions increased with age. The most prevalent clinical category of dementia was dementia of Alzheimer type, which represented 1.8% and 3-8% of these two age groups. The corresponding figures for vascular dementia were 0.4% and 0.9% and for secondary dementia 0.4% and 0.5%. Age-associated memory impairment is an age-dependent disorder with a high prevalence among the elderly; some of these patients may represent an early stage of Alzheimer's disease, suggesting that the prevalence of this disorder may be higher than previously estimated.
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页码:973 / 976
页数:4
相关论文
共 25 条
[1]   MAGNETIC-RESONANCE-IMAGING .2. CLINICAL USES [J].
ARMSTRONG, P ;
KEEVIL, SF .
BRITISH MEDICAL JOURNAL, 1991, 303 (6794) :105-109
[2]   ASSOCIATION BETWEEN QUANTITATIVE MEASURES OF DEMENTIA AND OF SENILE CHANGE IN CEREBRAL GREY MATTER OF ELDERLY SUBJECTS [J].
BLESSED, G ;
TOMLINSON, BE ;
ROTH, M .
BRITISH JOURNAL OF PSYCHIATRY, 1968, 114 (512) :797-+
[3]  
CORIA F, 1987, AM J PATHOL, V129, P422
[4]  
CORIA F, 1992, J NEUROL, V239, pS66
[5]   Age-Associated Memory Impairment: Proposed Diagnostic Criteria and Measures of Clinical Change - Report of a National Institute of Mental Health Work Group [J].
Crook, Thomas ;
Bartus, Raymond T. ;
Ferris, Steven H. ;
Whitehouse, Peter ;
Cohen, Gene D. ;
Gershon, Samuel .
DEVELOPMENTAL NEUROPSYCHOLOGY, 1986, 2 (04) :261-276
[6]   PREVALENCE OF ALZHEIMERS-DISEASE IN A COMMUNITY POPULATION OF OLDER PERSONS - HIGHER THAN PREVIOUSLY REPORTED [J].
EVANS, DA ;
FUNKENSTEIN, H ;
ALBERT, MS ;
SCHERR, PA ;
COOK, NR ;
CHOWN, MJ ;
HEBERT, LE ;
HENNEKENS, CH ;
TAYLOR, JO .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1989, 262 (18) :2551-2556
[7]  
Fleiss JL., 1981, STAT METHODS RATES P, V2
[8]   MINI-MENTAL STATE - PRACTICAL METHOD FOR GRADING COGNITIVE STATE OF PATIENTS FOR CLINICIAN [J].
FOLSTEIN, MF ;
FOLSTEIN, SE ;
MCHUGH, PR .
JOURNAL OF PSYCHIATRIC RESEARCH, 1975, 12 (03) :189-198
[9]   CEREBRAL BLOOD-FLOW IN DEMENTIA [J].
HACHINSKI, VC ;
ILIFF, LD ;
ZILHKA, E ;
DUBOULAY, GH ;
MCALLISTER, VL ;
MARSHALL, J ;
RUSSELL, RWR ;
SYMON, L .
ARCHIVES OF NEUROLOGY, 1975, 32 (09) :632-637
[10]   A RATING SCALE FOR DEPRESSION [J].
HAMILTON, M .
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1960, 23 (01) :56-62