THE ROLE OF C-MYC IN CELL-GROWTH

被引：374

作者：

EVAN, GI ^{[1
]}

LITTLEWOOD, TD ^{[1
]}

机构：

[1] IMPERIAL CANC RES FUND, LONDON WC2A 3PX, ENGLAND

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1993年 / 3卷 / 01期

关键词：

D O I：

10.1016/S0959-437X(05)80339-9

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Recent experiments have established that the c-myc oncogene encodes a sequence-specific DNA-binding protein that interacts with a specific intracellular partner, Max, and probably manifests its effects through transcriptional modulation. In addition, the range of biological functions attributed to expression of c-myc has grown to include not only transformation and mitogenesis but also cell death.

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页码：44 / 49

页数：6

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